Elevating the Entourage Effect

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Elevating the Entourage Effect

If you’re a cannabis nerd like we are, you might already be familiar with the Entourage Effect. An understanding of this essential cannabis concept...

If you’re a cannabis nerd like we are, you might already be familiar with the Entourage Effect. An understanding of this essential cannabis concept helps us understand how different types of cannabis products create different experiences and effects.

Researchers have identified hundreds of compounds in cannabis. While we understand the primary effects of the most common compounds like THC and CBD, we have not yet been able to explain precisely how these components work together to produce different reactions. One common theory, the Entourage Effect, explains that some cannabis compounds that have minimal or no effect in isolation may generate significant effects when combined with additional cannabinoids and terpenes. Put simply, the beneficial impact of the whole plant is greater than the sum of its individual parts.

This may explain why whole plant cannabis is reported to be so effective in treating certain medical conditions, while synthetically derived formulations of isolated THC or CBD often achieve less consistently positive patient outcomes. Researchers have explored the concept of synergy in herbal medicine for millennia; the idea that combining two or more compounds to create a magnified effect is nothing new. Synergy also explains why nutritional supplements tend to be less beneficial than eating fresh fruits and vegetables that contain a broad variety of vitamins and minerals.

So we can all agree that the Entourage Effect is a great thing. But how do we take advantage of it? Any properly grown cannabis will feature a full spectrum of cannabinoids and terpenes. However, when that cannabis is refined into concentrate or products, most – if not all – of the beneficial terpenes and other compounds will be lost to the extraction process. Whether using solvents like ethanol, butane or hexane, traditional methods like cold water extraction, or even common CO2 technologies, preserving quality terpenes through the extraction process has generally been considered impossible.

At Evolab, we see impossible as a challenge. When we realized that traditional extraction processes were neglecting the full spectrum of the plant that would benefit our customers, we sought out a new way of processing that would maintain those beneficial compounds.

Through collaborative partnerships and significant investment in research and development, we created the cannabis industry’s first clean CO2 extraction solution that not only preserves terpenes, but also allows us to extract the entire profile of any plant, enabling us to deliver the power of the Entourage Effect in convenient vape pens and extracts. Furthermore, this approach provides the unique ability to extract only the terpenes when we choose to, which led to the first and only product line featuring pure cannabis terpene profiles: FreshTerps™.

Creating the best extracts starts long before we bring raw material into our laboratory. Just like anything, what you put in dictates what you get out. This is especially true with cannabis processing. That’s why we only source the best material from the most respected cultivators that have been carefully and consistently optimizing their operations for years. We visit farms to understand the people and practices behind the material we use. We meticulously inspect every facility that we source from – analyzing consistency, genetics, pesticide use, cultivation methodologies, testing standards and much more. Then we sample, test and test some more – looking for good things like cannabinoid and terpene levels, and things that we avoid – like microbial contamination and pesticides.

Click here to read the full article on The Marijuana Times